Dispense in tight containers. Food and Drug Administration. In the tabulations that follow, a COSTART-based Dictionary terminology has been used to classify reported adverse reactions. If the COSTART term for a reaction was so general as to be uninformative, it was replaced with a more informative term when possible. The frequencies presented, therefore, represent the proportion of the total patient exposures to multiple doses of fluvoxamine maleate who experienced a reaction of the type cited on at least one occasion while receiving fluvoxamine maleate. Activated charcoal should be administered. Due to the large volume of distribution of this drug, forced diuresis, dialysis, hemoperfusion, and exchange transfusion are unlikely to be of benefit. No specific antidotes for fluvoxamine are known. generic droxia dosage for dogs droxia
For instance, Barsky says, a hypochondriac needs to resist the compulsion to self-diagnose and to seek assurance from doctors and friends. The best one can do is to get regular medical treatment from a trustworthy doctor trust and to live a healthy life. So far, no studies have been conducted on just how hypochondriacs use the Internet, Fallon says. But the phenomenon is common enough to have a snappy name -- "cyberchondria. Don't really notice any side effects. However it really reduced my racing thoughts my anxiety and overall calmer mood. DR. took me off it cold turkey in 2006 4 weeks later I had 3 grand maul seizures. Dr put me back on and the Luvox starting working in about 6 weeks. In 2012 Dr reduced from 100 mg twice a day to 50 mg twice a day 6 weeks later had another grand maul seizure. Dr raise the dose back to 100 mg twice a day and have not had any seizures since. Also we have no history of seizures in the previous three generations of both sides of our family's and three generations beneath me no one has ever had a recorded seizure. I never had any seizure's except when the DR took me off cold turkey and then even tried cutting half over a 4 month period.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Carbamazepine: Elevated carbamazepine levels and symptoms of toxicity have been reported with the coadministration of immediate-release fluvoxamine maleate tablets and carbamazepine. Skin: Infrequent: alopecia, dry skin, exfoliative dermatitis, furunculosis, seborrhea, skin discoloration.
LCR 150 on the other side of the cap. Luvox CR Capsules in placebo-controlled trials. Urogenital System: Infrequent: anuria, cystitis, delayed menstruation 1, dysuria, female lactation 1, hematuria, menopause 1, metrorrhagia 1, nocturia, premenstrual syndrome 1, urination impaired, vaginitis 1; Rare: kidney calculus, hematospermia 2, oliguria.
Fluvoxamine is usually taken at night. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended. Use with caution. The effects may be increased because of slower removal of the medicine from the body. The following symptoms, anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia psychomotor restlessness hypomania, and mania, have been reported in adult and pediatric patients being treated with antidepressants for major depressive disorder as well as for other indications, both psychiatric and nonpsychiatric. Alcohol: Studies involving single 40 g doses of ethanol oral administration in one study and intravenous in the other and multiple dosing with immediate-release fluvoxamine maleate tablets 50 mg given twice daily revealed no effect of either drug on the pharmacokinetics or pharmacodynamics of the other. As with other psychotropic medications, patients should be advised to avoid alcohol while taking Luvox CR Capsules. You should not take fluvoxamine if you are allergic to it, or if you are also using alosetron, pimozide, ramelteon, thioridazine, tizanidine, or methylene blue injection. Patients should be advised that taking Luvox CR can cause mild pupillary dilation, which in susceptible individuals, can lead to an episode of angle closure glaucoma. Pre-existing glaucoma is almost always open-angle glaucoma because angle closure glaucoma, when diagnosed, can be treated definitively with iridectomy. Open-angle glaucoma is not a risk factor for angle closure glaucoma. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of fluvoxamine in the elderly. However, elderly patients are more likely to have hyponatremia low sodium in the blood and liver problems, which may require an adjustment in the dose for patients receiving fluvoxamine. Dialysis is not expected to remove this drug. Luvox fluvoxamine is a used to treat or obsessive-compulsive disorders. Blue No. 2, Opacode Grey, red iron oxide, titanium dioxide gelatin porcine- or bovine-derived sugar spheres, and talc. Luvox CR Capsules are gluten-free. Hemic and Lymphatic Systems: Infrequent: leukocytosis, lymphadenopathy, thrombocytopenia; Rare: leukopenia, purpura. Pediatric Subjects: The pharmacokinetics of Luvox CR Capsules have not been evaluated in pediatric patients. However, the multiple-dose pharmacokinetics of fluvoxamine were determined in male and female children ages 6-11 and adolescents ages 12-17. Steady-state plasma fluvoxamine concentrations were 2- to 3-fold higher in children than in adolescents. Nervous System: Frequent: amnesia, apathy, hyperkinesia, hypokinesia, manic reaction, myoclonus, psychotic reaction; Infrequent: agoraphobia, akathisia, ataxia, CNS depression, convulsion, delirium, delusion, depersonalization, dyskinesia, dystonia, emotional lability, euphoria, extrapyramidal syndrome, gait unsteady, hallucinations, hemiplegia, hostility, hypersomnia, hypochondriasis, hypotonia, hysteria, increased libido, paralysis, paranoid reaction, phobia, psychosis, stupor, twitching, vertigo; Rare: akinesia, coma, fibrillations, mutism, obsessions, reflexes decreased, slurred speech, tardive dyskinesia, torticollis, trismus, withdrawal syndrome. Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of fluvoxamine tablets in children 8 to 17 years of age. Because fluvoxamine may cause weight loss or a decrease in appetite, children who will be taking fluvoxamine for a long time should have their weight and growth measured by the doctor regularly. Capsules should not be crushed or chewed.
Side Effects List Luvox Tablet side effects by likelihood and severity. Cardiovascular System: Frequent: hypotension; Infrequent: angina pectoris, bradycardia, cardiomyopathy, cardiovascular disease, cold extremities, conduction delay, myocardial infarction, pallor, pulse irregular, ST segment changes; Rare: AV block, cerebrovascular accident, embolus, pericarditis, phlebitis, pulmonary infarction, supraventricular extrasystoles. How should I take Luvox CR Capsules? Additionally, there was an approximate 25% decrease in nausea. In in vitro studies, fluvoxamine maleate had no significant affinity for histaminergic, alpha or beta adrenergic, muscarinic, or dopaminergic receptors. Antagonism of some of these receptors is thought to be associated with various sedative, cardiovascular, anticholinergic, and extrapyramidal effects of some psychotropic drugs. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist. probenecid
An examination of population subgroups from this trial did not reveal any clear evidence of a differential maintenance effect on the basis of age or gender. Some say that levels of exposure generally considered safe for most people can have an effect on a few. Do not take an MAOI within 2 weeks of stopping Luvox CR Capsules unless directed to do so by your physician. Avoid drinking alcohol with fluvoxamine. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. Special Senses: Infrequent: accommodation abnormal, conjunctivitis, diplopia, eye pain, mydriasis, otitis media, parosmia, visual field defect; Rare: corneal ulcer. The effectiveness of immediate-release fluvoxamine maleate tablets for the treatment of OCD was demonstrated in two 10-week multicenter, parallel group studies of adult outpatients. SSRIs and SNRIs, including Luvox CR Capsules, may increase the risk of bleeding events. Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs, warfarin, and other anticoagulants may add to this risk. Case reports and epidemiological studies case-control and cohort design have demonstrated an association between use of drugs that interfere with serotonin reuptake and the occurrence of gastrointestinal bleeding. Bleeding events related to SSRIs and SNRIs use have ranged from ecchymoses, hematomas, epistaxis, and petechiae to life-threatening hemorrhages. This can lead to serious trouble for hypochondriacs using the vast and unregulated web. No reports involved the administration of methylene blue by other routes such as oral tablets or local tissue injection or at lower doses. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Do not stop taking any medications without consulting your healthcare provider. Smokers had a 25% increase in the metabolism of fluvoxamine compared to nonsmokers.
Low salt sodium levels in the blood. Elderly people may be at greater risk for this. Luvox CR Capsules and other antidepressant medicines may increase suicidal thoughts or actions in some children, teenagers, or young adults within the first few months of treatment or when the dose is changed. This table shows the percentage of patients in each group who had at least one occurrence of a reaction at some time during their treatment. Reported adverse reactions were classified using a COSTART-based Dictionary terminology. Based on the number of females. Patients receiving Luvox CR Capsules should be advised to notify their physicians if they are breast-feeding an infant. As in adults, both children and adolescents exhibited nonlinear multiple-dose pharmacokinetics. Female children showed significantly higher AUC 0-12 and C max compared to male children and, therefore, lower doses of immediate-release fluvoxamine maleate tablets may produce therapeutic benefit see . No gender differences were observed in adolescents. Psychiatric: Patients should be monitored for discontinuation symptoms, and for worsening and emergence of suicidal thoughts. where to get zocor in singapore
Get emergency medical help if you have signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Use and dose must be determined by your doctor. It is likely that this experience significantly underestimates the degree of accumulation that might occur with repeated diazepam administration. Moreover, as noted with alprazolam, the effect of fluvoxamine may even be more pronounced when it is administered at higher doses. Hyponatremia may occur as a result of treatment with SSRIs and SNRIs, including Luvox CR Capsules. In many cases, this hyponatremia appears to be the result of the syndrome of inappropriate antidiuretic hormone secretion SIADH. In addition, patients should be advised to notify their physicians if they are taking, or plan to take, any prescription or over-the-counter drugs, since there is a potential for clinically important interactions with Luvox CR Capsules. Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Propranolol and Other Beta-Blockers: Coadministration of immediate-release fluvoxamine maleate tablets 100 mg per day and propranolol 160 mg per day in normal volunteers resulted in a mean five-fold increase range 2 to 17 in minimum propranolol plasma concentrations. In this study, there was a slight potentiation of the propranolol-induced reduction in heart rate and reduction in the exercise diastolic pressure. In addition, the numbers of implantations and embryos were decreased at the highest dose. Diltiazem: Bradycardia has been reported with the coadministration of immediate-release fluvoxamine maleate tablets and diltiazem. Depression or other serious mental illnesses are the most important causes of suicidal thoughts or actions.
Tell your healthcare provider about all the medicines that you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Luvox CR Capsules and some medicines may interact with each other, may not work as well, or may cause serious side effects. Prescribers or other health professionals should inform patients, their families, and their caregivers about the benefits and risks associated with treatment with Luvox CR Capsules and should counsel them in the appropriate use. A patient Medication Guide discussing antidepressant medicines, depression and other serious mental illnesses, and suicidal thoughts or actions and other important information about Luvox CR Capsules is available for Luvox CR Capsules. The prescriber or health professional should instruct patients, their families, and their caregivers to read both sections of the Medication Guide and should assist them in understanding its contents. Patients should be given the opportunity to discuss the contents of the Medication Guide and to obtain answers to any questions they may have. The complete text of the Medication Guide is reprinted at the end of this document. Lithium: As with other serotonergic drugs, lithium may enhance the serotonergic effects of fluvoxamine and, therefore, the combination should be used with caution. Seizures have been reported with the coadministration of immediate-release fluvoxamine maleate tablets and lithium. Opioid withdrawal symptoms were reported following fluvoxamine maleate discontinuation in another patient. No good doctor will order an every time your ears are ringing or a every time your stomach's upset. Based on the number of males. Relapse during the double-blind phase was defined as an increase in the Y-BOCS score of at least 30% over the baseline for that phase or patient refusal to continue treatment due to a substantial increase in OCD symptoms. In the double-blind phase, patients receiving continued immediate-release fluvoxamine maleate tablets treatment experienced, on average, a significantly lower relapse rate than those receiving placebo. The patient fully recovered. Bioavailability: A single-dose crossover study in 28 healthy subjects was conducted to compare the pharmacokinetics of fluvoxamine after administration of Luvox CR Capsules and immediate-release fluvoxamine maleate tablets. Incidence based on number of male patients. cheapest finasteride buy online shopping
Only some people are at risk for these problems. You may want to undergo an eye examination to see if you are at risk and receive preventative treatment if you are. Total daily doses of more than 50 mg should be given in two divided doses. If the two divided doses are not equal, the larger dose should be given at bedtime. Mostly feeling warm, hot, or flushed. How very low levels of chemical exposure affect people isn't clear. Approximately 230 patients and 5 patients participating in controlled premarketing studies with immediate-release fluvoxamine maleate tablets and Luvox CR Capsules, respectively, were 65-years of age or over. No overall differences in safety were observed between these patients and younger patients. Other reported clinical experience has not identified differences in response between the elderly and younger patients. NSAIDs, like ibuprofen or naproxen or aspirin. Monoamine Oxidase Inhibitor MAOI. Ask your healthcare provider or pharmacist if you are not sure if you take an MAOI, including the antibiotic linezolid. Decreased fetal body weight was seen at the high dose. Swallow the extended-release capsule whole. However, there is substantial evidence from placebo-controlled maintenance trials in adults with depression that the use of antidepressants can delay the recurrence of depression. Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. What is Luvox CR Capsules? Do not start Luvox CR Capsules in a patient who is being treated with linezolid or intravenous methylene blue because there is an increased risk of serotonin syndrome. Ask your healthcare professional how you should dispose of any medicine you do not use.
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. This section provides information on the proper use of a number of products that contain fluvoxamine. It may not be specific to Luvox. Please read with care. Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using fluvoxamine. Your family or other caregivers should also be alert to changes in your mood or symptoms. While it is difficult to know the precise risk of sexual dysfunction associated with the use of SSRIs, health care providers should routinely inquire about such possible side effects. Safety and efficacy in patients younger than 18 years other than pediatric patients with Obsessive Compulsive Disorder OCD have not been established. Special Senses: Infrequent: dry eyes, photophobia, taste loss. Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Don't really notice any side effects. However it really reduced my racing thoughts my anxiety and overall calmer mood. DR. took me off it cold turkey in 2006 4 weeks later I had 3 grand maul seizures. Dr put me back on and the Luvox starting working in about 6 weeks. Keep the Luvox CR Capsules bottle closed tightly. There are no specific laboratory tests recommended. Do not suddenly stop taking this medicine without checking with your doctor first. Your doctor may want you to gradually reduce the amount you are taking before stopping it completely. This is to decrease the chance of having withdrawal symptoms such as agitation, confusion, headache, irritability, numbness or tingling, restlessness, trouble sleeping, or unusual drowsiness or weakness. Contrary to what some skeptics think, hypochondriacs are not pretending or just trying to get attention. Multiple hepatic cytochrome P450 isoenzymes are involved in the oxidative biotransformation of a large number of structurally different drugs and endogenous compounds. The available knowledge concerning the relationship of fluvoxamine and the cytochrome P450 isoenzyme system has been obtained mostly from pharmacokinetic interaction studies conducted in healthy volunteers, but some preliminary in vitro data are also available. imuran
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. In the controlled clinical trials with 403 patients treated with Luvox CR Capsules, there was one nonfatal intentional overdose. Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. During premarketing clinical trials conducted in North America and Europe, multiple doses of Luvox CR Capsules or immediate-release fluvoxamine maleate tablets were administered for a combined total of 3219 patient exposures in patients suffering OCD or other studied disorders. These exposures include 482 patient exposures with Luvox CR Capsules and 2737 patient exposures with immediate-release fluvoxamine maleate tablets. Untoward reactions associated with this exposure were recorded by clinical investigators using descriptive terminology of their own choosing. Exploratory analyses for age and gender effects on outcomes did not show any significant differential responsiveness on the basis of age or sex. Luvox CR Capsules may be taken with or without food. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Patients should be advised to notify their physicians if they develop a rash, hives, or a related allergic phenomenon during therapy with Luvox CR Capsules. This drug is not approved for use in pediatric patients except for patients with obsessive compulsive disorder OCD. Barsky, "since that feeling of relief doesn't last anyway. The metabolism of fluvoxamine has not been fully characterized and the effects of potent cytochrome P450 isoenzyme inhibition, such as the ketoconazole inhibition of CYP3A4, on fluvoxamine metabolism have not been studied. N-desmethyldiazepam to a level that was too low to measure over the course of the 2-week-long study. You could have more side effects than usual if you use these medicines together. The concomitant use of Luvox CR Capsules with MAOIs intended to treat psychiatric disorders is contraindicated. Luvox CR should also not be started in a patient who is being treated with MAOIs such as linezolid or intravenous methylene blue. This medicine may increase your risk for bleeding problems. The stress that goes along with this worry can make the symptoms even worse. Triptans: There have been rare postmarketing reports of serotonin syndrome with use of an SSRI and a triptan. What should I avoid while taking Luvox CR Capsules? It is very important that your doctor check your progress at regular visits. This will allow for changes in the dose and to help reduce any side effects. atlanta drug store eldepryl
Food caused the mean AUC and C max of fluvoxamine to increase only slightly; therefore, administration of Luvox CR Capsules with food does not significantly affect the absorption of fluvoxamine. The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply. If propranolol or metoprolol is coadministered with Luvox CR Capsules, a reduction in the initial beta-blocker dose and more cautious dose titration are recommended. No dosage adjustment is required for Luvox CR Capsules. Pimozide is metabolized by the CYP3A4 isozyme and it has been demonstrated that ketoconazole, a potent inhibitor of CYP3A4, blocks the metabolism of this drug, resulting in increased plasma concentrations of parent drug. An increased plasma concentration of pimozide causes QT prolongation and has been associated with torsades de pointes-type ventricular tachycardia, sometimes fatal. As noted below, a substantial pharmacokinetic interaction has been observed for fluvoxamine in combination with alprazolam, a drug that is known to be metabolized by the CYP3A4 isozyme. Although it has not been definitively demonstrated that fluvoxamine is a potent CYP3A4 inhibitor, it is likely to be, given the substantial interaction of fluvoxamine with alprazolam. The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions.
Tryptophan: Tryptophan may enhance the serotonergic effects of fluvoxamine, and the combination should, therefore, be used with caution. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Other notable signs and symptoms seen with immediate-release fluvoxamine maleate overdose single or multiple drugs include bradycardia, ECG abnormalities such as heart arrest, QT interval prolongation, first degree atrioventricular block, bundle branch block, and junctional rhythm convulsions, dizziness, liver function disturbances, tremor, and increased reflexes. In vitro data suggest that fluvoxamine is a relatively weak inhibitor of CYP2D6. Luvox CR Capsules can cause sleepiness or may affect your ability to make decisions, think clearly, or react quickly. You should not drive, operate heavy machinery, or do other dangerous activities until you know how Luvox CR Capsules affect you. Do not drink alcohol while using Luvox CR Capsules. arot.info gemfibrozil
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Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use Luvox CR Capsules for a condition for which it was not prescribed. Do not give Luvox CR Capsules to other people, even if they have the same condition. It may harm them. Theophylline: The effect of steady-state immediate-release fluvoxamine maleate tablets 50 mg tablets given twice daily on the pharmacokinetics of a single dose of theophylline 375 mg as 442 mg aminophylline was evaluated in 12 healthy non-smoking, male volunteers. The clearance of theophylline was decreased approximately 3-fold. Therefore, if theophylline is coadministered with fluvoxamine maleate, its dose should be reduced to one-third of the usual daily maintenance dose and plasma concentrations of theophylline should be monitored. No dosage adjustment is required for Luvox CR Capsules. pharmacy alfuzosin interaction alfuzosin
Luvox CR is the same kind of medicine as those used to treat depression. Tell your doctor all medications and supplements you use. Fluvoxamine can pose a risk of problems to an unborn baby and should be taken by pregnant women only when the potential benefits of the drug outweigh the risks to the fetus. Fluvoxamine is secreted in human breast milk. The decision of whether to discontinue nursing or to discontinue the drug should take into account the potential for serious adverse effects from exposure to fluvoxamine in the nursing infant. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.
Side Effects List Fluvoxamine MALEATE side effects by likelihood and severity. Those feelings are real. But they can happen for many reasons. The question is whether MCS is an illness. Alprazolam - When immediate-release fluvoxamine maleate tablets 100 mg given once daily and alprazolam 1 mg given 4 times per day were coadministered to steady state, plasma concentrations and other pharmacokinetic parameters AUC, C max, T ½ of alprazolam were approximately twice those observed when alprazolam was administered alone; oral clearance was reduced by about 50%. The elevated plasma alprazolam concentrations resulted in decreased psychomotor performance and memory. This interaction, which has not been investigated using higher doses of fluvoxamine, may be more pronounced if a 300 mg daily dose is coadministered, particularly since fluvoxamine exhibits non-linear pharmacokinetics over the dosage range 100-300 mg. If alprazolam is coadministered with Luvox CR Capsules, the initial alprazolam dosage should be at least halved and titration to the lowest effective dose is recommended. No dosage adjustment is required for Luvox CR Capsules.
If you take too much Luvox CR, call your healthcare provider or poison control center right away, or get emergency treatment. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Changes in appetite or weight. Children and adolescents should have height and weight monitored during treatment. In some cases, a patient already receiving Luvox CR therapy may require urgent treatment with linezolid or intravenous methylene blue. If acceptable alternatives to linezolid or intravenous methylene blue treatment are not available and the potential benefits of linezolid or intravenous methylene blue treatment are judged to outweigh the risks of serotonin syndrome in a particular patient, Luvox CR should be stopped promptly, and linezolid or intravenous methylene blue can be administered. The patient should be monitored for symptoms of serotonin syndrome for two weeks or until 24 hours after the last dose of linezolid or intravenous methylene blue, whichever comes first.